Preheat oven to 500 degrees and put the rack in the lower portion of the oven.
Using a can of spray oil, spray either a deep dish pizza pan or an 9' x 13" baking dish, preferably aluminum or tin.
Take the pizza dough and gently start molding it to the bottom of the tin. It will not stretch all the way, just try to get it as far as you can. Set it aside to warm to room temperature to relax the dough.
Meanwhile, make the sauce. In a skillet over medium heat, add the olive oil and minced garlic, oregano and pepper flakes and cook until fragrant, about 30 seconds.
Add in the tomatoes and spices, salt, and sugar and bring to a simmer. Cook for about 30 minutes or until slightly reduced.
After 30 minutes, stretch out the dough again, removing air bubbles as you go. Make sure the dough touches the edge of the pan. Do this by stretching it past the pan, so that it shrinks to size.
Add a layer of sauce, spooning over the entire pizza.
Add a layer of pepperoni evenly over the top.
Add a layer of cheese. Make sure that the cheese extends the entire pizza and touches the edges of the pan.
Add another sauce/pepperoni/cheese layer. (Optional.)
Spoon more sauce over the top in three rows. (Optional.)
Add a light sprinkling of oregano and red pepper flakes (if you want the pizza to be a little spicy.)
Transfer to oven and bake for 12-15 minutes or until the top is golden and bubbly, and the edges are black and crispy .(If you have more layers, err towards a longer time.)
Transfer to a cold stove top or trivets. Using a spatula or knife, loosen the edges of the pizza. Then use a pizza cutter to cut even squares.
Serve immediately.